![]() Excitement surrounded DCD LT resulted in rapid growth in the number of transplants performed from 1994 until 2007 (Fig. Resurgence of DCD LT was first described by groups from Pittsburgh and Wisconsin in the mid-1990s. Following the acceptance of declaration of death according to neurologic criteria as a legal entity, most countries including the USA almost exclusively utilized DBD donors until the 1990s. Prior to the development of the Harvard criteria for brain death in 1968, all deceased organ donors were declared deceased using circulatory arrest criteria and thus represented the first DCD organ transplants performed. The present review describes the changing landscape of DCD LT. ![]() More recent single center publications from high volume DCD programs have demonstrated equivalent outcomes between DCD and DBD liver transplantation (LT), with appropriate donor and recipient selection. Since those initial publications, there have been substantial developments in the understanding of how to effectively utilize DCD livers. These inferior results were ascribed to high rates of biliary complications, as well as increased rates of primary non-function and hepatic artery thrombosis. Initial reports examining the use of liver grafts from DCD described inferior long-term outcomes when compared with donation after brain death donors (DBD). ![]() Donation after circulatory death (DCD) donor livers represents one potential means to help address this discordance. The transplant community continues to look for ways to help address the discordance between donor liver graft availability and patients on the liver transplant waiting list.
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